lunedì 31 ottobre 2011

giovedì 6 ottobre 2011

mercoledì 28 settembre 2011

Il tumore del cavo orale è tra le forme tumorali più diffuse al mondo, altamente invasivo e invalidante. Gli studi di questi ultimi anni dimostrano che una diagnosi precoce aumenta la probabilità di curare questo tipo di tumore con il minimo danno e senza gravi deformazioni del volto.

Il tumore del cavo orale rappresenta globalmente circa il 4% di tutti i tumori maligni nell'uomo e l'1% nelle donne. In Italia l'incidenza è in media di 8,44 nuovi casi ogni 100.000 abitanti maschi all'anno e di 2,22 per le femmine. In Gran Bretagna – ha rilevato il Cancer Research (l'organismo deputato a rilevare la situazione dei tumori) – le diagnosi di cancro alle vie orali sono aumentate del 28% negli uomini attorno ai 40 anni e del 20% nei giovani fino a 30 anni. Tale incremento è dovuto al consumo esagerato di sostanze alcoliche e superalcoliche. Negli ultimi anni il tasso di mortalità è in lento ma costante aumento a tutte le età e segue quello delle neoplasie polmonari, con le quali condivide alcune cause.

Le cause scatenanti sono principalmente ambientali come l´esposizione a cancerogeni di natura chimica, agenti virali, alimentazioni inadeguate, traumatismo cronico dovuto, per esempio, a protesi dentarie mal realizzate, scarsa igiene del cavo orale, cause genetiche e sistemiche. Tra queste, in particolare, il Papilloma Virus (HPV) rappresenta uno dei principali fattori di rischio anche fra i giovani di entrambi, in quanto trasmissibile attraverso il sesso orale non protetto e con partners multipli. Il rischio di carcinoma orale è da 6 a 28 volte superiore nei fumatori e aumenta se si associa al consumo di alcolici; fra le sostanze cancerogene quelle maggiormente implicate sono gli idrocarburi aromatici policiclici e le amine aromatiche, residui della combustione del tabacco.

La prevenzione, una corretta igiene orale e stili di vita sani sono alla base per impedire l´insorgere della malattia.


14 – 31 maggio 2011
Oral Cancer Day

Un'iniziativa di
Fondazione Onlus

mercoledì 6 luglio 2011

Alghe miracolose contro l'obesità

In USA il primo trattamento senza chirurgia per combattere l'obesità
http://www.gastrobioring.com/home.html

martedì 12 aprile 2011

Cardiovascular Disease

 

Study shows no association between dietary saturated fats and cardiovascular disease risk

A reduction in dietary saturated fatty acids has generally been acknowledged to improve cardiovascular health, but in a recently published study, no link could be established between intake levels of saturated fatty acids and a risk for cardiovascular disease.
A group of researchers from the Children's Hospital Oakland Research Institute in Oakland, California and the Departments of Nutrition and Epidemiology at Harvard School of Public Health in Boston, Massachusetts, performed a meta-analysis of prospective epidemiologic studies on saturated fatty acid intake and risk of coronary heart disease, stroke, or cardiovascular disease in general. In prospective epidemiologic studies a group of initially healthy people, a cohort, is followed over time to investigate if occurrence of disease is related to the exposure of certain factors e.g. dietary and other lifestyle factors. In a meta-analysis, results from different studies on a specific topic are collected and jointly analysed in order to reach a general conclusion based on the accumulated scientific data. Twenty-one studies matched the inclusion criteria for the current meta-analysis. Together these comprised 347,747 individuals of which some 11,000 developed any cardiovascular disease. The results of the analysis showed no significant association between high intake of saturated fatty acids and an increased risk of coronary heart disease, stroke or cardiovascular disease. Age, sex, and study quality were factors taken into account in the analysis, but they did not impact on the outcome.

The analysis was limited to prospective studies that can be used to study associations, but cannot clarify cause and effect. Nevertheless, the results from this meta-analysis are in line with the existing knowledge that only reducing the intake of saturated fatty acids is not likely to have major beneficial effects on the risk for cardiovascular disease. Previous studies including clinical trials however indicate that a reduction in cardiovascular disease risk will be obtained by replacing a major part of the dietary saturated fatty acids with polyunsaturated fatty acids, which is in agreement with the conclusions of a recent consultation paper on fats and health by the World Health Organization (WHO) and the Food and Agriculture Organization (FAO). Both findings from previous epidemiological studies and clinical trials support that substituting saturated fatty acids with polyunsaturated fatty acids is more beneficial for cardiovascular disease risk than replacing the saturated fatty acids with carbohydrates. In the current meta-analysis no conclusions could be drawn on the effects on cardiovascular disease risk of replacing saturated fatty acids with either polyunsaturated fatty acids or carbohydrates, since among the studies included in the analysis only a few addressed this hypothesis. The authors themselves acknowledge that their analysis is not suited (‘More data are needed’) to determine whether cardiovascular disease risk is likely to be influenced by the specific nutrients used to replace saturated fatty acids.
Fat is an essential component of our diet; we all need to eat certain amounts to stay in good health. But, it is not only the total amount of fat that is important, we also need to think about what kind of fats we choose to eat. In general, we should eat more of the ‘good’ unsaturated fats, including essential omega-3 polyunsaturated fatty acids and monounsaturated fatty acids and less of the ‘bad fats’, such as certain saturated fatty acids. Studies have shown that a high consumption of certain saturated fatty acids may increase the levels of ‘bad’ LDL-cholesterol in the blood, but this is not the case with all saturated fatty acids. Elevated blood levels of LDL-cholesterol is a known risk factor for cardiovascular disease.
The recommendation to persons who wish to reduce their risk of cardiovascular disease is to replace the saturated fatty acids in their diet with polyunsaturated fatty acids. It is considered that a diet with around 30% of daily energy coming from fat is consistent with good health, with a maximum of 10-11% from saturated fatty acids.
For more information:

Siri-Tarino PW, Sun Q et al. (2010). "Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease." Am J Clin Nutr. Published ahead of print on January 13, 2010; doi: 10.3945/ajcn.2009.27725

Joint FAO/WHO Expert Consultation on fats and fatty acids in human nutrition – background paper: Skeaff CM, Miller J (2009). “Dietary Fat and Coronary Heart Disease: Summary of Evidence from Prospective Cohort and Randomised Controlled Trials” Ann Nutr Metab 2009;55:173–201; doi: 10.1159/000229002
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